Publication List

  1. Xu J, Mercado-Lopez X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, Lopez CB. Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I. MBio.(2015) 6:e01265-15.
  2. Bursztejn AC, Briggs TA, Del Toro Duany Y, Anderson BH, O'Sullivan J, Williams SG, Bodemer C, Fraitag S, Gebhard F, Leheup B, Lemelle I, Oojageer A, Raffo E, Schmitt E, Rice GI, Hur S, Crow YJ., Unusual cutaneous features associated with a heterozygous gain-of-function mutation in IFIH1: Aicardi-Goutières-Singleton-Merten overlapping syndrome. Br J Dermatol. Epub ahead of print.
  3. Ahmad S and Hur S, Helicases in antiviral immunity: dual properties as sensors and effectors. Trends in Biochemical Sciences (2015) 40:576-85. (Review)
  4. Wu B, Houh Y & Hur S, Measuring Monomer-to-Filament Transition of MAVS as an In Vitro Activity Assay for RIG-I-Like Receptors, Methods Molecular Biology, Vol 1390, In Press, (Book Chapter)
  5. Wu B & Hur S, How RIG-I like receptors activate MAVS. Curr. Opin. Virol. (2015) 12:91-8
  6. Yao H, Dittmann M, Peisley A, Hoffmann H-H, Gilmore RH, Schmidt T, Schmidt-Burgk J, Hornung V, Rice CM, and Hur S, ATP-dependent effector-like functions of RIG-I like receptors. Molecular Cell, (2015), 58:541-8. --Highlighted in Science Signaling (2015), 8:ec130
  7. Del Toro Duany Y, Wu B and Hur S, MDA5-filament, dynamics and disease. Curr. Opin. Virol. (2015), 12:20-5 (Review)
  8. Wu B, Peisley A, Tetrault D, Li Z, Egelman EH, Magor, KE, Walz T, Penczek PA and Hur S, Molecular imprinting as a signal activation mechanism of the viral RNA sensor RIG-I. Molecular Cell, (2014), 55: 511-23. --Highlighted in Molecular Cell (2014), 55:505-7
  9. Rice GI*, del Toro Duany Y*, Jenkinson EM, Forte GMA, Anderson BH, Ariaudo G, Bader-Meunier B, Baildam EM, Battini R, Beresford MW, Casarano M, Chouchane M, Cimaz R, Collins AE, Cordeiro NJV, Dale RC, Davidson JE, De Waele L, Desguerre I, Faivre L, Fazzi E, Isidor B, Lagae L, Latchman AR, Lebon P, Li C, Livingston JH, Lourenco CM, Mancardi MM, Masurel-Paulet A, McInnes IB, Menezes MP, Mignot C, O’Sullivan J, Orcesi S, Picco PP, Riva E, Robinson RA, Rodrigues D, Salvatici E, Scott C, Szybowska M, Tolmie JL, Vanderver A, Vanhulle C, Vieira JP, Webb K, Whitney RN, Williams SG, Wolfe LA, Zuberi SM,  Hur S**, Crow YJ**. Gain of function mutations in IFIH1 (MDA5) cause a spectrum of human disease phenotypes associated with an upregulation of type I interferon signaling. Nature Genetics, (2014), 46:503-9, (* co-first authors, ** co-corresponding authors). --Highlighted in Nature Genetics (2014), 84:1551-61
  10. Peisley A, Wu B, Xu H, Chen ZJ & Hur S. Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I. Nature, (2014), 509:110-4  -- Highlighted in Cell Research (2014), 24:645-6
  11. Peisley A*, Wu B*, Yao H, Walz T & Hur S. RIG-I forms signaling-competent filaments in an ATP-dependent and ubiquitin-independent manner. Molecular Cell, (2013), 51, 573-83, PMID: 23993742 (* equal contribution) -- Highlighted in Faculty1000Prime
  12. Wu B and Hur S. Viral counterattack against the host innate immune system. Cell Research, (2013), 23, 735-6, PMID:23478300 (Review)
  13. Wu B, Peisley A, Richards C, Yao H, Zeng Z, Lin C, Chu F, Walz T & Hur S. Structural Basis for dsRNA recognition, filament formation and antiviral signaling by MDA5. Cell, (2013) 152, 276-89,  PMID: 23273991 -- Highlighted in Nat. Rev. Immunol. (2013), 13:153
  14. Feng Q, Hato SV, Langereis MA, Zoll J, Virgen-Slane R, Peisley A, Hur S, Semler BL, van Rij R & van Kuppeveld FJM. MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells, Cell Reports, (2012), 2, 1187-96, PMID:23142662
  15. Peisley A*, Jo MH*, Lin C, Wu B, Orme-Johnson M, Walz T, Hohng S & Hur S. Kinetic Mechanism for Viral dsRNA Length Discrimination by MDA5 filament. Proc. Natl. Acad. Sci. U.S.A. (2012), 109, E3340-9, PMID:23129641 (* equal contribution)
  16. Peisley A & Hur S. Multi-level regulation of cellular recognition of viral dsRNA. Cell Mol. Life Sci. (2013), 70, 1949-63, PMID:22960755 (Review)
  17. Peisley A, Lin C, Wu B, Orme-Johnson M, Liu M, Walz T & Hur S. Cooperative Assembly and Dynamic Disassembly of MDA5 Filaments for Viral dsRNA Recognition. Proc. Natl. Acad. Sci. U.S.A. (2011), 108, 21010-5.